Some people, especially those with health issues or over-reactive immune systems, may have adverse or allergic reactions to substances such as uncomfortable physical or cognitive effects, or over-sensitivity. If contradictory information about dosage is found, one should always start from the lowest in order minimize the risk. Another factor to consider is substance purity which can differ between batches of product.įor information on the appropriate dosage for any substance, research should be done using a combination of PsychonautWiki, Erowid, Tripsit, Wikipedia, Bluelight, and Google. This minimizes the risk of an accidental negative experience enormously it is important to remember that everybody reacts differently to every substance depending on factors such as their own personal tolerance, brain chemistry, body weight, metabolism, stomach contents, and personal sensitivity. ![]() ![]() So please be patient with new substances! The dose should never be doubled or tripled as this vastly increases the likelihood of either a bad trip or side effects such as anxiety, panic attacks, and psychosis. Also, 2C-P can have a very slow onset if ingested, and peak effects reportedly do not occur for 3 to 5 hours. For example, 2C-P is known to have a steep dose-response curve, as little as a few extra milligrams separating a manageable dose and an overdose. However, some substances are notable tricky to work with. It is advised to increase the amount in controlled increments, usually adding 1/3 to 1/2 the previous dose. This allows the user to verify that their bodies are compatible with the substance and do not exhibit any allergies or unusual sensitivity.Īfter the initial test, the user may decide to increase the dosage. An inexperienced user should always start at a lower dosage with the goal of working their way up to a normal or common dose. The user should avoid dosages that they are uncomfortable or unfamiliar with.
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